Gene Associated With Language, Speech And Reading Disorders Identified

Description

Gene Associated With Language, Speech And Reading Disorders Identified

ScienceDaily (Aug. 28, 2009) — A new candidate gene for Specific Language Impairment has been identified by a research team directed by Mabel Rice at the University of Kansas, in collaboration with Shelley Smith, University of Nebraska Medical Center, and Javier Gayán of Neocodex, Seville, Spain.

The finding, reported in the current issue of the Journal of Neurodevelopmental Disorders , was discovered by examining genes previously identified as candidate genes for reading impairments or speech sound disorders.

The results point toward the likelihood of multiple genes contributing to language impairment, some of which also contribute to reading or speech impairment.

A gene on Chromosome 6 – KIAA0319 – was associated with variability in language abilities in a study of children with Specific Language Impairment (SLI) and their family members, as well as with variability in speech and reading abilities. Children with SLI who were selected for the study had no hearing loss, general intellectual deficit or autism.

Language ability involves vocabulary and grammar, whereas speech involves the accuracy of sound production. Both language and speech ability contribute to a child's ability to read. The finding that a candidate gene could influence all three abilities suggests a common pathway that could contribute to overlapping strengths or deficiencies across speech, language and reading.

According to Rice, "We don't understand the biological mechanisms yet but ...

Original URL

http://www.sciencedaily.com/releases/2009/08/090827123319.htm

http://www.sciencedaily.com/releases/2009/08/090827123319.htm